Tuesday, October 04, 2011

Lisinopril Conversion to ACE-Is and ARBs

 

Approximate to Lisinopril 5mg

Equivalent to Lisinopril 10mg

Approximate to Lisinopril 20mg

Approximate to Lisinopril 40mg

Approximate to Lisinopril 80mg

Captopril

--

25mg BID

50mg BID

100mg BID

200mg BID

Enalapril

5mg

10mg

20mg

40mg

--

Ramipril

1.25mg

2.5mg

5mg

10mg

20mg

Benazepril

5mg

10mg

20mg

40mg

80mg

Fosinopril**

--

10mg

20mg

40mg

80mg

Moexipril

3.75mg

7.5mg

15mg

30mg

60mg

Perindopril

2mg

4mg

8mg

16mg

--

Trandolapril

0.5mg

1mg

2mg

4mg

4mg BID

Quinapril

5mg

10mg

20mg

40 mg

80mg

Candesartan

4mg

8mg

8-16mg

--

--

Valsartan

40mg

80mg

160mg

--

--

Losartan

25mg

50mg

100mg

--

--

Irbesartan

75mg

150mg

300mg

--

--

Olmesartan

5mg

10mg

20mg

--

--

Telmisartan

--

20mg

40mg

--

--

Lisinopril Conversion to ACE-Is and ARBs


 


 

*Approximate dosing was based off of ratios from known equivalent lisinopril doses

**If cough with lisinopril, Fosinopril (cough 2%-10%) may be used before switching to ARB


 


 


 


 


 


 

Kathryn Ley, our last pharmacy student, put this chart together.  Hopefully, it can serve as a good starting point. 


 

References:

Angiotensin converting enzyme (ACE) inhibitor antihypertensive dose comparison. Pharmacist's Letter/Prescriber's Letter 2009;25(8):250801.

Angiotensin receptor blocker (ARB) antihypertensive dose comparison. Pharmacist's Letter/Prescriber's Letter 2009;25(8):250801.

Diovan [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corp; 2011.

Lexi-Comp Online, Lexi-Drugs Online, Hudson, Ohio: Lexi-Comp, Inc.; 2011; September 12, 2011.